This is a fascinating read but i need to point out it's
not yet peer reviewed so take it with a pinch of salt at the moment.
All i can tell you is that in layman's terms it makes perfect sense to explain why i fell into a pit of pain yet my wife who i slept with at the same time has had no symptoms at all, so far.
Previous Endemic Coronavirus Encounters Linked With Long COVIDhttps://www.medscape.com/viewarticle/982283?src=wnl_recnlnew2_ous_221013_MSCPEDIT_&uac=431499HY&impID=4745878Fyi, my original source for this was from Friendly Pharmacy 5 on YouTube, a long standing source that i've followed for longer than i can remember due to my experience with Long Covid, a Canadian pharmacist who has helped me in more ways than she will ever know.
https://www.youtube.com/channel/UCFhP_Yn_5xF0_bRDmaG_5qg/community?lb=UgkxhU9G6zBcVvdfcCpxuHZ4_rUufFpR4PgkIf i've read the paper correct then what appears to have happened is exposure at some point to SARS-COV-1 or a Coronavirus common cold/flu has confused the immune system to trigger a response to a COV-1 virus when in fact the body has been infected with SARS-COV-2, allowing SARS-COV-2 to run rampant within the body.
I'm no expert on any of this but i remember when SARS-COV-1 was around and i never really paid much attention to it, that said i was working in a front-line service industry so i could well have been exposed to it and not known... it may also be that at some point in my lifetime i was exposed to a Coronavirus strain of the common cold/flu that some others weren't exposed too? e.g. The longer you live the greater the chance of exposure to other coronavirus's, explaining why it effects older people more (but not exclusively).
So many unanswered questions but this appears to be a huge first step, it also has the potential to be huge for not only Long Covid but also for ME/CFS etc.